Earth’s ionosphere has long been targeted as a medium for remote sensing of explosive terrestrial events such as earthquakes, volcanic eruptions, and nuclear/conventional weapon detonations. Until now, the only confirmed ionospheric detections have been of very large events that were easily detectable through other traditional global sensor systems (e.g., seismic). We present the first clear, confirmed detections of relatively low yield 1-ton TNT-equivalent chemical explosions using pulsed Doppler radar observations of isodensity layers in the ionospheric E region. The shape and spectra of the detected waveforms closely match predictions from the acoustic ray tracing and weakly nonlinear waveform propagation models. The explosions were roughly three orders of magnitude lower yield than any previous confirmed ionospheric detection and represent the first conclusive evidence that explosions of this size can have clear impacts on the ionosphere. This technique could improve the remote detection of both anthropogenic and natural explosive events.